Photodynamic bubble-generating microneedles for enhanced transdermal cancer therapy

• Main Authors: Ning, Xiaoyu, Chen, Si, Yang, Yating, Hwang, Jangsun, Wiraja, Christian, Zhang, Chi, Liu, Wei, Liu, Linbo, Xu, Chenjie
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Engineering::Nanotechnology; Bubble-Generating Microneedles; Frozen Immersion
• Online Access: https://hdl.handle.net/10356/162431
• Institution: Nanyang Technological University

Active bubble-generating microneedles (MNs) upon skin interstitial fluid (ISF) contact facilitate deeper and more efficient delivery of intradermal therapeutics. However, bubble-generating MN platforms are sensitive to moisture, which limits their variety to load various functional drugs. This artic...