Discovering the permeation through the outer membrane of gram-negative bacteria using molecular dynamics simulations

• Main Author: Deylami, Javad
• Other Authors: Yong Ee Hou
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Medicine::Computer applications; Science::Biological sciences::Biophysics; Science::Chemistry::Biochemistry
• Online Access: https://hdl.handle.net/10356/162657
• Institution: Nanyang Technological University

We are in the age of the antibiotic resistance, and the pharmaceutical industry faces a crisis. The trend of antibiotic resistant leads to over-prescribing antibiotics because general practitioners perceiving a greater risk in not prescribing antibi- otics compared with their unnecessary use. Conseq...