Activatable polymeric nanoprobe for near-infrared fluorescence and photoacoustic imaging of T lymphocytes

• Main Authors: Zhang, Yan, He, Shasha, Chen, Wan, Liu, Yinghua, Zhang, Xuefei, Miao, Qingqing, Pu, Kanyi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Immunotherapy; Nanoparticles
• Online Access: https://hdl.handle.net/10356/162802
• Institution: Nanyang Technological University

Development of real-time non-invasive imaging probes to assess infiltration and activation of cytotoxic T cells (CTLs) is critical to predict the efficacy of cancer immunotherapy, which however remains challenging. Reported here is an activatable semiconducting polymer nanoprobe (SPNP) for near-infr...