Molecular mechanism of human anti-Zika non-structural protein 1 antibodies

• Main Author: Ho, Jun Sheng
• Other Authors: Luo Dahai
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/162962
• Institution: Nanyang Technological University

Zika virus (ZIKV) is an arthropod-transmitted flavivirus that has seen significant outbreaks globally, with the potential to cause neurological or birth abnormalities. There remains a large unmet need for efficacious vaccines and antivirals against ZIKV. Recently, four monoclonal antibodies (mAbs...