Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L)

• Main Authors: Leow, Melvin Khee-Shing, Rengaraj, Anantharaj, Narasimhan, Kothandaraman, Verma, Sanjay K., Yaligar, Jadegoud, Thu, Giang Le Thi, Sun, Lijuan, Goh, Hui Jen, Govindharajulu, Priya, Sadananthan, Suresh Anand, Michael, Navin, Meng, Wei, Gallart-Palau, Xavier, Sun, Lei, Karnani, Neerja, Sze, Siu Kwan, Velan, S. Sendhil
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Science::Biological sciences; Mitochondrial Protein; Brown Adipose Tissue
• Online Access: https://hdl.handle.net/10356/162999
• Institution: Nanyang Technological University

Brown adipose tissue (BAT) is a promising weapon to combat obesity and metabolic disease. BAT is thermogenic and consumes substantial amounts of glucose and fatty acids as fuel for thermogenesis and energy expenditure. To study BAT function in large human longitudinal cohorts, safe and precise detec...