Analysis and characterization of nervous system defects in candidate mutations resulting from a mutagenesis screen in the fruit fly, Drosophila melanogaster

• Main Author: Joanita Jasmen
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• Online Access: http://hdl.handle.net/10356/16308
• Institution: Nanyang Technological University

Parkinson’s disease (PD) is characterised by the selective loss of dopaminergic (DA) neurons in the midbrain. A potential strategy to treat PD involves directing stem cell differentiation into DA progenitors. Before this can be achieved, there is a need to identify additional genes that regulate DA...