Ionic regulation of mycobacterial infection by potassium and potassium channel
Epigenetic analysis of monocytes from active TB patients demonstrated enrichment of KCNJ15, which encodes an inwardly rectifying K+ channel (Kir4.2). We investigated the function of Kir4.2 in mycobacterial infection using a gain and loss-of-function approach and knockout mouse model. Kir4.2 was obse...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2022
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Online Access: | https://hdl.handle.net/10356/163110 |
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Institution: | Nanyang Technological University |
Language: | English |