A dual-mode NADH biosensor based on gold nanostars decorated CoFe₂ metal–organic frameworks to reveal dynamics of cell metabolism

• Main Authors: Zhao, Xiaoping, Niu, Ruoxin, Fan, Shu, Jing, Xunan, Gao, Rui, Yang, Hongbo, Wang, Heng, Wang, Daquan, Yang, Zhiwei, Xie, Yunchuan, She, Junjun, Chen, Peng, Meng, Lingjie
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Surface-Enhanced Raman Scattering; Metal−Organic Frameworks
• Online Access: https://hdl.handle.net/10356/163134
• Institution: Nanyang Technological University

Nicotinamide adenine dinucleotide (NADH) is central to metabolism and implicated in various diseases. Herein, nanohybrids of gold nanostars and metal-organic frameworks are devised and demonstrated as a dual-mode NADH sensor, for which colorimetric detection is enabled by its peroxidase-like nanozym...