Modulated TRPC1 expression predicts sensitivity of breast cancer to doxorubicin and magnetic field therapy: segue towards a precision medicine approach

• Main Authors: Tai, Yee Kit, Chan, Karen Ka Wing, Fong, Charlene Hui Hua, Ramanan, Sharanya, Yap, Jasmine Lye Yee, Yin, Jocelyn Naixin, Yip, Yun Sheng, Tan, Wei Ren, Koh, Angele Pei Fern, Tan, Nguan Soon, Chan, Ching Wan, Huang, Ruby Yun Ju, Li, Jing Ze, Fröhlich, Jürg, Franco-Obregón, Alfredo
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Breast Cancer; Patient-Derived Xenograft
• Online Access: https://hdl.handle.net/10356/163189
• Institution: Nanyang Technological University

Chemotherapy is the mainstream treatment modality for invasive breast cancer. Unfortunately, chemotherapy-associated adverse events can result in early termination of treatment. Paradoxical effects of chemotherapy are also sometimes observed, whereby prolonged exposure to high doses of chemotherapeu...