Cell surface nucleolin is a novel ADAMTS5 receptor mediating endothelial cell apoptosis

A Disintegrin and Metalloproteinase with ThromboSpondin motif (ADAMTS) 5 functions as an anti-angiogenic and anti-cancer protein independent of its metalloproteinase activity. Both full-length ADAMTS5 and TS5-p45, the autocatalytically cleaved C-terminal 45 kDa truncate of ADAMTS5, inhibits angiogen...

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Bibliographic Details
Main Authors: Kirman, Dogan Can, Renganathan, Bhuvanasundar, Chui, Wai Kit, Chen, Ming Wei, Kaya, Neslihan Arife, Ge, Ruowen
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163244
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Institution: Nanyang Technological University
Language: English