Unveiling potential mechanisms of Spatholobi Caulis against lung metastasis of malignant tumor by network pharmacology and molecular docking

Lung metastasis of malignant tumor signifies worse prognosis and immensely deteriorates patients' life quality. Spatholobi Caulis (SC) has been reported to reduce lung metastasis, but the mechanism remains elusive.

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Bibliographic Details
Main Authors: Xie, Feiyu, Wang, Mina, Su, Yixin, Xiao, Kunmin, Chu, Xuelei, Long, Sidan, Li, Linlu, Zhang, Xin, Xue, Peng, Zhu, Shijie
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/163262
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Institution: Nanyang Technological University
Language: English
Description
Summary:Lung metastasis of malignant tumor signifies worse prognosis and immensely deteriorates patients' life quality. Spatholobi Caulis (SC) has been reported to reduce lung metastasis, but the mechanism remains elusive.