Light-triggered hypoxia-responsive nanoscale metal-organic frameworks for highly efficient antitumor treatment

• Main Authors: Yang, Guangbao, Bindra, Anivind Kaur, Phua, Fiona Soo Zeng, Liu, Jiawei, Wu, Hongwei, Wang, Dongdong, Qian, Cheng, Liu, Guofeng, Zhao, Yanli
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Chemistry; Cancer Treatment; Hypoxia
• 在線閱讀: https://hdl.handle.net/10356/163324

Photodynamic therapy (PDT), as a noninvasive therapeutic tool, can result in a high level of hypoxia in tumors. Herein, hypoxia-responsive nanoscale metal-organic frameworks (UiO-AZB) are prepared, which contain an azo group in its organic linker. After modifying the surface of UiO-AZB with chlorin...