Gold nanoparticle conjugated magnetic beads for extraction and nucleation based signal amplification in lateral flow assaying

• Main Authors: Sharma, Antareep, Tok, Alfred Iing Yoong, Alagappan, Palaniappan, Liedberg, Bo
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials::Biomaterials; Lateral Flow Assay; Gold Nanoparticles
• Online Access: https://hdl.handle.net/10356/163410
• Institution: Nanyang Technological University

Analogues and interferents present in complex matrices like blood, plasma or serum influence lateral flow assay (LFA) responses, resulting in weak signals which compromise the limit of detection. Herein, we report a gold nanoparticle conjugated magnetic bead (GMB) based LFA approach for extraction a...