Enaminone formation drives the coupling of biosynthetic pathways to generate cyclic lipopeptides

A family of novel cyclic lipopeptides named tasikamides A H (Tsk A H) were discovered recently in Streptomyces tasikensis P46. Aside from the unique cyclic pentapeptide scaffold shared by the tasikamides, Tsk A C contain a hydrazone bridge that connects the cyclic pentapeptide to the lipophil...

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Bibliographic Details
Main Authors: Candra, Hartono, Ma, Guang-Lei, Lee, Sean Qiu En, Liang, Zhao-Xun
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/163433
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Institution: Nanyang Technological University
Language: English