Characterization of autosomal recessive Parkinson disease-linked parkin mutations.

• Main Author: Ng, Xiao Hui.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/16354
• Institution: Nanyang Technological University

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder affecting millions of elderly people worldwide. While the majority of PD cases occur in a sporadic manner, a subset of PD cases is attributable to genetic mutations. Among these, mutations in parkin have been identified...