Reclassifying tumour cell cycle activity in terms of its tissue of origin

• Main Authors: Lundberg, Arian, Jong, Joan Jing Yi, Lindström, Linda S., Tobin, Nicholas P.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Science::Medicine; Androgen Receptor; Adenocarcinoma
• Online Access: https://hdl.handle.net/10356/163573
• Institution: Nanyang Technological University

Genomic alterations resulting in loss of control over the cell cycle is a fundamental hallmark of human malignancies. Whilst pan-cancer studies have broadly assessed tumour genomics and their impact on oncogenic pathways, analyses taking the baseline signalling levels in normal tissue into account a...