Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses

The enteric mycobiota is a major component of the human gut microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a meta-analysis to uncover the contribution of the fungal mycobiota to CRC.

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Main Authors:	Lin, Yufeng, Lau, Harry Cheuk-Hay, Liu, Yali, Kang, Xing, Wang, Yiwei, Ting, Nick Lung-Ngai, Kwong, Thomas Ngai-Yeung, Han, Jing, Liu, Weixin, Liu, Changan, She, Junjun, Wong, Sunny Hei, Sung, Joseph Jao Yiu, Yu, Jun
Other Authors:	Lee Kong Chian School of Medicine (LKCMedicine)
Format:	Article
Language:	English
Published:	2022
Subjects:	Science::Medicine Enteric Mycobiota Colorectal Cancer
Online Access:	https://hdl.handle.net/10356/163679
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-163679
record_format	dspace
spelling	sg-ntu-dr.10356-1636792023-03-05T16:51:42Z Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses Lin, Yufeng Lau, Harry Cheuk-Hay Liu, Yali Kang, Xing Wang, Yiwei Ting, Nick Lung-Ngai Kwong, Thomas Ngai-Yeung Han, Jing Liu, Weixin Liu, Changan She, Junjun Wong, Sunny Hei Sung, Joseph Jao Yiu Yu, Jun Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Enteric Mycobiota Colorectal Cancer The enteric mycobiota is a major component of the human gut microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a meta-analysis to uncover the contribution of the fungal mycobiota to CRC. Published version This study was supported by National Key R&D Program of China (No. 2020YFA0509200/2020YFA0509203); Research Grants Council-Collaborative Research Fund Hong Kong (C4039-19G, C7065-18GF and 14110819, 14111621), and the Vice-Chancellor’s Discretionary Fund Chinese University of Hong Kong. 2022-12-13T08:46:47Z 2022-12-13T08:46:47Z 2022 Journal Article Lin, Y., Lau, H. C., Liu, Y., Kang, X., Wang, Y., Ting, N. L., Kwong, T. N., Han, J., Liu, W., Liu, C., She, J., Wong, S. H., Sung, J. J. Y. & Yu, J. (2022). Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses. Gastroenterology, 163(4), 908-921. https://dx.doi.org/10.1053/j.gastro.2022.06.038 0016-5085 https://hdl.handle.net/10356/163679 10.1053/j.gastro.2022.06.038 35724733 2-s2.0-85136136528 4 163 908 921 en Gastroenterology © 2022 The Author(s). Published by Elsevier Inc. on behalf of the AGA Institute. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Medicine Enteric Mycobiota Colorectal Cancer
spellingShingle	Science::Medicine Enteric Mycobiota Colorectal Cancer Lin, Yufeng Lau, Harry Cheuk-Hay Liu, Yali Kang, Xing Wang, Yiwei Ting, Nick Lung-Ngai Kwong, Thomas Ngai-Yeung Han, Jing Liu, Weixin Liu, Changan She, Junjun Wong, Sunny Hei Sung, Joseph Jao Yiu Yu, Jun Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
description	The enteric mycobiota is a major component of the human gut microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a meta-analysis to uncover the contribution of the fungal mycobiota to CRC.
author2	Lee Kong Chian School of Medicine (LKCMedicine)
author_facet	Lee Kong Chian School of Medicine (LKCMedicine) Lin, Yufeng Lau, Harry Cheuk-Hay Liu, Yali Kang, Xing Wang, Yiwei Ting, Nick Lung-Ngai Kwong, Thomas Ngai-Yeung Han, Jing Liu, Weixin Liu, Changan She, Junjun Wong, Sunny Hei Sung, Joseph Jao Yiu Yu, Jun
format	Article
author	Lin, Yufeng Lau, Harry Cheuk-Hay Liu, Yali Kang, Xing Wang, Yiwei Ting, Nick Lung-Ngai Kwong, Thomas Ngai-Yeung Han, Jing Liu, Weixin Liu, Changan She, Junjun Wong, Sunny Hei Sung, Joseph Jao Yiu Yu, Jun
author_sort	Lin, Yufeng
title	Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
title_short	Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
title_full	Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
title_fullStr	Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
title_full_unstemmed	Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
title_sort	altered mycobiota signatures and enriched pathogenic aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses
publishDate	2022
url	https://hdl.handle.net/10356/163679
_version_	1759855960171479040

Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses

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