Bone bricks: the effect of architecture and material composition on the mechanical and biological performance of bone scaffolds

• Main Authors: Daskalakis, Evangelos, Huang, Boyang, Vyas, Cian, Acar, Anil A., Liu, Fengyuan, Fallah, Ali, Cooper, Glen, Weightman, Andrew, Blunn, Gordon, Koç, Bahattin, Bartolo, Paulo
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Mechanical engineering; Regeneration; Degradation
• Online Access: https://hdl.handle.net/10356/164238
• Institution: Nanyang Technological University

Large bone loss injuries require high-performance scaffolds with an architecture and material composition resembling native bone. However, most bone scaffold studies focus on three-dimensional (3D) structures with simple rectangular or circular geometries and uniform pores, not able to recapitulate...