Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization

There is limited data on the mechanisms of aspirin desensitization in patients with nonsteroidal anti-inflammatory drug (NSAID)-induced urticaria/angioedema (NIUA).

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Main Authors: Tay, Sen Hee, Santosa, Amelia, Goh, Eugene Chen Howe, Xu, Chun Xiang, Wu, Lik Hang, Bigliardi-Qi, Mei, Pakkiri, Leroy Sivappiragasam S/O., Lee, Bernett, Drum, Chester Lee, Bigliardi, Paul Lorenz
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/164304
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1643042023-03-05T16:53:47Z Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization Tay, Sen Hee Santosa, Amelia Goh, Eugene Chen Howe Xu, Chun Xiang Wu, Lik Hang Bigliardi-Qi, Mei Pakkiri, Leroy Sivappiragasam S/O. Lee, Bernett Drum, Chester Lee Bigliardi, Paul Lorenz Lee Kong Chian School of Medicine (LKCMedicine) Singapore Immunology Network, A*STAR Centre for Biomedical Informatics Science::Medicine Desensitization Preaspirin Desensitization There is limited data on the mechanisms of aspirin desensitization in patients with nonsteroidal anti-inflammatory drug (NSAID)-induced urticaria/angioedema (NIUA). Published version This work was supported by a grant from Thermo Fisher Scientific. 2023-01-16T01:33:08Z 2023-01-16T01:33:08Z 2022 Journal Article Tay, S. H., Santosa, A., Goh, E. C. H., Xu, C. X., Wu, L. H., Bigliardi-Qi, M., Pakkiri, L. S. S., Lee, B., Drum, C. L. & Bigliardi, P. L. (2022). Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization. Journal of Allergy and Clinical Immunology, 150(6), 1486-1497. https://dx.doi.org/10.1016/j.jaci.2022.07.025 0091-6749 https://hdl.handle.net/10356/164304 10.1016/j.jaci.2022.07.025 35964779 2-s2.0-85138209537 6 150 1486 1497 en Journal of Allergy and Clinical Immunology © 2022 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Desensitization
Preaspirin Desensitization
spellingShingle Science::Medicine
Desensitization
Preaspirin Desensitization
Tay, Sen Hee
Santosa, Amelia
Goh, Eugene Chen Howe
Xu, Chun Xiang
Wu, Lik Hang
Bigliardi-Qi, Mei
Pakkiri, Leroy Sivappiragasam S/O.
Lee, Bernett
Drum, Chester Lee
Bigliardi, Paul Lorenz
Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
description There is limited data on the mechanisms of aspirin desensitization in patients with nonsteroidal anti-inflammatory drug (NSAID)-induced urticaria/angioedema (NIUA).
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Tay, Sen Hee
Santosa, Amelia
Goh, Eugene Chen Howe
Xu, Chun Xiang
Wu, Lik Hang
Bigliardi-Qi, Mei
Pakkiri, Leroy Sivappiragasam S/O.
Lee, Bernett
Drum, Chester Lee
Bigliardi, Paul Lorenz
format Article
author Tay, Sen Hee
Santosa, Amelia
Goh, Eugene Chen Howe
Xu, Chun Xiang
Wu, Lik Hang
Bigliardi-Qi, Mei
Pakkiri, Leroy Sivappiragasam S/O.
Lee, Bernett
Drum, Chester Lee
Bigliardi, Paul Lorenz
author_sort Tay, Sen Hee
title Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
title_short Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
title_full Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
title_fullStr Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
title_full_unstemmed Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
title_sort distinct transcriptomic and metabolomic profiles characterize nsaid-induced urticaria/angioedema patients undergoing aspirin desensitization
publishDate 2023
url https://hdl.handle.net/10356/164304
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