Quantifying systematic RBE-weighted dose uncertainty arising from multiple variable RBE models in organ at risk

• Main Authors: Koh, Calvin Wei Yang, Tan, Hong Qi, Ng, Yan Yee, Lin, Yen Hwa, Ang, Khong Wei, Lew, Wen Siang, Lee, James Cheow Lei, Park, Sung Yong
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Physics; Science::Medicine; Cancer Patient; Clinical Target Volume
• Online Access: https://hdl.handle.net/10356/164317
• Institution: Nanyang Technological University

Purpose: Relative biological effectiveness (RBE) uncertainties have been a concern for treatment planning in proton therapy, particularly for treatment sites that are near organs at risk (OARs). In such a clinical situation, the utilization of variable RBE models is preferred over constant RBE model...