Childhood antibiotics as a risk factor for Crohn's disease: the ENIGMA international cohort study

• Main Authors: Mak, Joyce W. Y., Yang, Sun, Stanley, Annalise, Lin, Xiaoqing, Morrison, Mark, Ching, Jessica Y. L., Niu, Junkun, Wilson-O'Brien, Amy L., Feng, Rui, Tang, Whitney, Hamilton, Amy L., Or, Leo, Trakman, Gina L., Lin, Winnie Y. Y., Sung, Joseph Jao Yiu, Chen, Ming Hu, Mao, Yinglei, Kamm, Michael A., Ng, Siew C.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Antibiotics; Crohn’s
• Online Access: https://hdl.handle.net/10356/164339
• Institution: Nanyang Technological University

Background and Aim: Environmental factors play a key role in development of Crohn's disease (CD), thought to be mediated by changes in the gut microbiota. We aimed to delineate the potential contribution of antibiotic exposure to subsequent development of CD, across diverse geographical populat...