Structure and protein recognition of G-quadruplexes

• Main Author: Ngo, Khac Huy
• Other Authors: Phan Anh Tuan
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Physics
• Online Access: https://hdl.handle.net/10356/164358
• Institution: Nanyang Technological University

G-rich oligonucleotides can adopt non-canonical secondary structures called G-quadruplexes (G4s) which are biologically relevant and found in applications and nanotechnology. Due to the high structural polymorphism, it is still a challenge to specifically target different G4 structures. In this stud...