Structure and protein recognition of G-quadruplexes

• المؤلف الرئيسي: Ngo, Khac Huy
• مؤلفون آخرون: Phan Anh Tuan
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Science::Physics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164358
• المؤسسة: Nanyang Technological University

G-rich oligonucleotides can adopt non-canonical secondary structures called G-quadruplexes (G4s) which are biologically relevant and found in applications and nanotechnology. Due to the high structural polymorphism, it is still a challenge to specifically target different G4 structures. In this stud...