Sustained activation of non-canonical NF-κB signalling drives glycolytic reprogramming in doxorubicin-resistant DLBCL

• المؤلفون الرئيسيون: Lim, Shen Kiat, Peng, Chen Chen, Low, Shannon, Vijay, Varsheni, Budiman, Andrea, Phang, Beng Hooi, Lim, Jing Quan, Jeyasekharan, Anand D., Lim, Soon Thye, Ong, Choon Kiat, Tan, Suet Mien, Li, Yinghui
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Cell Signalling; Non-Hodgkin Lymphoma
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164468

DLBCL is the most common lymphoma with high tumor heterogeneity. Treatment refractoriness and relapse from R-CHOP therapy in patients remain a clinical problem. Activation of the non-canonical NF-κB pathway is associated with R-CHOP resistance. However, downstream targets of non-canonical NF-κB medi...