Stage-dependent differential influence of metabolic and structural networks on memory across Alzheimer's disease continuum

• Main Authors: Ng, Kok Pin, Qian, Xing, Ng, Kwun Kei, Ji, Fang, Rosa-Neto, Pedro, Gauthier, Serge, Kandiah, Nagaendran, Zhou, Helen Juan
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Alzheimer Disease; Brain Metabolism
• Online Access: https://hdl.handle.net/10356/164534
• Institution: Nanyang Technological University

Background: Large-scale neuronal network breakdown underlies memory impairment in Alzheimer’s disease (AD). However, the differential trajectories of the relationships between network organisation and memory across pathology and cognitive stages in AD remain elusive. We determined whether and how th...