Evaluating primary endpoints for COVID-19 therapeutic trials to assess recovery

• المؤلفون الرئيسيون: Douin, David J., Siegel, Lianne, Grandits, Greg, Phillips, Andrew, Aggarwal, Neil R., Baker, Jason, Brown, Samuel M., Chang, Christina C., Goodman, Anna L., Grund, Birgit, Higgs, Elizabeth S., Hough, Catherine L., Murray, Daniel D., Paredes, Roger, Parmar, Mahesh, Pett, Sarah, Polizzotto, Mark N., Sandkovsky, Uriel, Self, Wesley H., Young, Barnaby Edward, Babiker, Abdel G., Davey, Victoria J., Kan, Virginia, Gelijns, Annetine C., Matthews, Gail, Thompson, B. Taylor, Lane, H. Clifford, Neaton, James D., Lundgren, Jens D., Ginde, Adit A.
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Medicine; COVID-19; Outcomes Assessment
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164556

Rationale: Uncertainty regarding the natural history of coronavirus disease (COVID-19) led to difficulty in efficacy endpoint selection for therapeutic trials. Capturing outcomes that occur after hospital discharge may improve assessment of clinical recovery among hospitalized patients with COVID-19...