Hydroxyapatite nanoparticles-cell interaction: new approaches to disclose the fate of membrane-bound and internalised nanoparticles

• Main Authors: Bonany, Mar, Pérez-Berná, Ana Joaquina, Dučić, Tanja, Pereiro, Eva, Martin-Gómez, Helena, Mas-Moruno, Carlos, van Rijt, Sabine, Zhao, Zhitong, Espanol, Montserrat, Ginebra, Maria-Pau
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Materials; Hydroxyapatite; Nanoparticles
• Online Access: https://hdl.handle.net/10356/164578
• Institution: Nanyang Technological University

Hydroxyapatite nanoparticles are popular tools in bone regeneration, but they have also been used for gene delivery and as anticancer drugs. Understanding their mechanism of action, particularly for the latter application, is crucial to predict their toxicity. To this end, we aimed to elucidate the...