Lipid-coated hybrid nanoparticles for enhanced bacterial biofilm penetration and antibiofilm efficacy

• Main Authors: Lee, Hiang Wee, Kharel, Sharad, Loo, Joachim Say Chye
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Materials; Engineering::Bioengineering; In-Vitro; Vancomycin
• Online Access: https://hdl.handle.net/10356/164632
• Institution: Nanyang Technological University

Up to 80% of all infections are biofilm-mediated and they are often challenging to treat as the underlying bacterial cells can become 100- to 1000-fold more tolerant toward antibiotics. Antibiotic-loaded nanoparticles have gained traction as a potential drug delivery system to treat biofilm infectio...