Parkin deficiency exacerbates fasting-induced skeletal muscle wasting in mice

• Main Authors: Peker, Nesibe, Sharma, Mridula, Kambadur, Ravi
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Metabolic Homeostasis; Ubiquitin
• Online Access: https://hdl.handle.net/10356/164654
• Institution: Nanyang Technological University

Parkinson's Disease (PD) is a chronic and progressive neurodegenerative disease manifesting itself with tremors, muscle stiffness, bradykinesia, dementia, and depression. Mutations of mitochondrial E3 ligase, PARKIN, have been associated with juvenile PD. Previous studies have characterized mus...