Electrospun aligned PCLl/gelatin scaffolds mimicking the skin ECM for effective antimicrobial wound dressings

• Main Authors: Ghomi, Erfan Rezvani, Lakshminarayanan, Rajamani, Chellappan, Vijila, Verma, Navin Kumar, Chinnappan, Amutha, Neisiany, Rasoul Esmaeely, Amuthavalli, Kottaiswamy, Poh, Zhi Sheng, Wong, Brandon Han Siang, Dubey, Nileshkumar, Narayan, Roger, Ramakrishna, Seeram
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Electrospinning; Wound Healing
• Online Access: https://hdl.handle.net/10356/164737
• Institution: Nanyang Technological University

Bacterial infections and multidrug-resistant bacteria are major health burdens in wound care. Biocompatible antimicrobial agents, e.g., ε-polylysine (ε-PL), provide a broad spectrum of antibacterial properties and support dermal cell growth. Here, ε-PL was incorporated into polycaprolactone (PCL)/ge...