Photocatalytic deconstructive aliphatic carbon–carbon bond cleavage and functionalization of unactivated alcohols

• Main Authors: Thanetchaiyakup, Adisak, Chin, Kek Foo, Ðokić, Miloš, Tan, Philip Mark Leetiong, Lin, Desmond Junjie, Mathiew, Mitch, Zhao, Xin, Heng, Jerry Zhi Xiong, Toh, Daryle Jun Xiong, Liu, Xue-Wei, Ramalingam, Balamurugan, Soo, Han Sen
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Photoredox Catalysis; Deconstructive Functionalization; Aliphatic Alcohol Substrates; Base-Metal Photocatalysis
• Online Access: https://hdl.handle.net/10356/164813
• Institution: Nanyang Technological University

Carbon–carbon (C–C) bonds are challenging to selectively cleave owing to their chemical inertness and omnipresence in organic molecules; however, they can be targeted during the late-stage modification of natural products and active pharmaceutical ingredients. Herein, we report a selective deconstru...