Ellipsoidal magnetic mesoporous particles for targeted drug delivery.

Ellipsoidal rattle-type hollow particles with hematite (α-Fe2O3) spindles encapsulated in mesoporous silica shells have been fabricated by simultaneous sol-gel polymerization of tetraethoxysilane (TEOS) and n-octadecyltrimethoxysilane (C18TMS). A ring-shaped cavity was created between the iron oxide...

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Main Author: Chia, Daryl De Yuan.
Other Authors: School of Chemical and Biomedical Engineering
Format: Final Year Project
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/16482
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-164822023-03-03T15:34:50Z Ellipsoidal magnetic mesoporous particles for targeted drug delivery. Chia, Daryl De Yuan. School of Chemical and Biomedical Engineering Lou, Xiong Wen DRNTU::Engineering::Chemical engineering::Biotechnology Ellipsoidal rattle-type hollow particles with hematite (α-Fe2O3) spindles encapsulated in mesoporous silica shells have been fabricated by simultaneous sol-gel polymerization of tetraethoxysilane (TEOS) and n-octadecyltrimethoxysilane (C18TMS). A ring-shaped cavity was created between the iron oxide core and mesoporous silica shell by hydrothermal treatment followed by calcination to remove the organic groups. A mesoporous silica shell with randomly ordered mesopores and a cavity of up to 40 nm wide was created. The fabrication of ellipsoidal particles with α-Fe2O3 core-mesoporous silica shell was also attempted through surface templating with the cationic surfactant cetyltrimethylammonium bromide (CTAB) as a template. The synthesized particles were sub-optimal as the process used to fabricate the particles was not yet mature. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-26T07:46:42Z 2009-05-26T07:46:42Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16482 en Nanyang Technological University 48 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering::Biotechnology
spellingShingle DRNTU::Engineering::Chemical engineering::Biotechnology
Chia, Daryl De Yuan.
Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
description Ellipsoidal rattle-type hollow particles with hematite (α-Fe2O3) spindles encapsulated in mesoporous silica shells have been fabricated by simultaneous sol-gel polymerization of tetraethoxysilane (TEOS) and n-octadecyltrimethoxysilane (C18TMS). A ring-shaped cavity was created between the iron oxide core and mesoporous silica shell by hydrothermal treatment followed by calcination to remove the organic groups. A mesoporous silica shell with randomly ordered mesopores and a cavity of up to 40 nm wide was created. The fabrication of ellipsoidal particles with α-Fe2O3 core-mesoporous silica shell was also attempted through surface templating with the cationic surfactant cetyltrimethylammonium bromide (CTAB) as a template. The synthesized particles were sub-optimal as the process used to fabricate the particles was not yet mature.
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Chia, Daryl De Yuan.
format Final Year Project
author Chia, Daryl De Yuan.
author_sort Chia, Daryl De Yuan.
title Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
title_short Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
title_full Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
title_fullStr Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
title_full_unstemmed Ellipsoidal magnetic mesoporous particles for targeted drug delivery.
title_sort ellipsoidal magnetic mesoporous particles for targeted drug delivery.
publishDate 2009
url http://hdl.handle.net/10356/16482
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