Growth hormone increases BDNF and mTOR expression in specific brain regions after photothrombotic stroke in mice

Growth hormone increases BDNF and mTOR expression in specific brain regions after photothrombotic stroke in mice

Aims. We have shown that growth hormone (GH) treatment poststroke increases neuroplasticity in peri-infarct areas and the hippocampus, improving motor and cognitive outcomes. We aimed to explore the mechanisms of GH treatment by investigating how GH modulates pathways known to induce neuroplasticity...

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Bibliographic Details
Main Authors: Sanchez-Bezanilla, Sonia, Beard, Daniel J., Hood, Rebecca J., Åberg, N. David, Crock, Patricia, Walker, Frederick R., Nilsson, Michael, Isgaard, Jörgen, Ong, Lin Kooi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Human Growth Hormone
Photothrombotic Stroke
Online Access:https://hdl.handle.net/10356/165120
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/165120

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