On-demand generation of peroxynitrite from an integrated two-dimensional system for enhanced tumor therapy

• Main Authors: Liu, Shikai, Li, Wenting, Chen, Hengxing, Zhou, Jialing, Dong, Shuming, Zang, Pengyu, Tian, Boshi, Ding, He, Gai, Shili, Yang, Piaoping, Zhao, Yanli
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; DNA Damage Repair; Glutamine Synthetase
• Online Access: https://hdl.handle.net/10356/165517
• Institution: Nanyang Technological University

Nanosystem-mediated tumor radiosensitization strategy combining the features of X-ray with infinite penetration depth and high atomic number elements shows considerable application potential in clinical cancer therapy. However, it is difficult to achieve satisfactory anticancer efficacy using clinic...