Tumor extracellular matrix-targeted nanoscavengers reverse suppressive microenvironment for cocktail therapy

• Main Authors: Chen, Xiaokai, Zhang, Xiaodong, Wu, Yinglong, Chen, Yun, Guo, Yi, Jana, Deblin, Wang, Dongdong, Yuan, Wei, Zhao, Yanli
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Nanomedicine; Calcium Ion Therapy
• Online Access: https://hdl.handle.net/10356/165553
• Institution: Nanyang Technological University

Extracellular matrix (ECM) is not only a natural bulwark to shield solid tumor cells from therapeutic agents and cytotoxic T lymphocytes (CTLs), but also one of the key factors that cause tumor hypoxic environment, severely hindering photodynamic reactions and immune responses. In this work, multifu...