From 2D to 3D: development of monolayer dopaminergic neuronal and midbrain organoid cultures for Parkinson's disease modeling and regenerative therapy

From 2D to 3D: development of monolayer dopaminergic neuronal and midbrain organoid cultures for Parkinson's disease modeling and regenerative therapy

Parkinson's Disease (PD) is a prevalent neurodegenerative disorder that is characterized pathologically by the loss of A9-specific dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of the midbrain. Despite intensive research, the etiology of PD is currently unresolved, and...

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Bibliographic Details
Main Authors: Yeap, Yee Jie, Tng, Teddy J. W., Lee, Mok Jung, Goh, Micaela, Lim, Kah-Leong
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Parkinson’s Disease
Pluripotent Stem Cells
Online Access:https://hdl.handle.net/10356/165606
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/165606

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