Effects of pressure drop on supercritical fluid chromatography.

This project investigates the effects of pressure drop on the physical properties changes of supercritical carbon dioxide in a chromatography column. Axial temperature measurements of the chromatography column were made with surface type thermocouples. The chromatography column is insulated with a c...

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Main Author: Lim, Lenard Junming.
Other Authors: Arvind Rajendran
Format: Final Year Project
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/16561
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-165612023-03-03T15:35:11Z Effects of pressure drop on supercritical fluid chromatography. Lim, Lenard Junming. Arvind Rajendran School of Chemical and Biomedical Engineering DRNTU::Science::Chemistry::Analytical chemistry::Chromatography This project investigates the effects of pressure drop on the physical properties changes of supercritical carbon dioxide in a chromatography column. Axial temperature measurements of the chromatography column were made with surface type thermocouples. The chromatography column is insulated with a cotton layer and kept in a Styrofoam container, and the entire chromatography column and insulation are housed within an oven. It is found out experimentally that the axial temperature change of CO2 decreases along the chromatography column. Numerical simulations were also performed to model the axial temperature gradient in the column. The simulations yielded a good approximation term when a heat transfer term is added; thereby validating that heat transfer through the column wall is important. These results are important to understand the dynamics of supercritical fluid chromatography system. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-27T03:29:10Z 2009-05-27T03:29:10Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16561 en Nanyang Technological University 50 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Chemistry::Analytical chemistry::Chromatography
spellingShingle DRNTU::Science::Chemistry::Analytical chemistry::Chromatography
Lim, Lenard Junming.
Effects of pressure drop on supercritical fluid chromatography.
description This project investigates the effects of pressure drop on the physical properties changes of supercritical carbon dioxide in a chromatography column. Axial temperature measurements of the chromatography column were made with surface type thermocouples. The chromatography column is insulated with a cotton layer and kept in a Styrofoam container, and the entire chromatography column and insulation are housed within an oven. It is found out experimentally that the axial temperature change of CO2 decreases along the chromatography column. Numerical simulations were also performed to model the axial temperature gradient in the column. The simulations yielded a good approximation term when a heat transfer term is added; thereby validating that heat transfer through the column wall is important. These results are important to understand the dynamics of supercritical fluid chromatography system.
author2 Arvind Rajendran
author_facet Arvind Rajendran
Lim, Lenard Junming.
format Final Year Project
author Lim, Lenard Junming.
author_sort Lim, Lenard Junming.
title Effects of pressure drop on supercritical fluid chromatography.
title_short Effects of pressure drop on supercritical fluid chromatography.
title_full Effects of pressure drop on supercritical fluid chromatography.
title_fullStr Effects of pressure drop on supercritical fluid chromatography.
title_full_unstemmed Effects of pressure drop on supercritical fluid chromatography.
title_sort effects of pressure drop on supercritical fluid chromatography.
publishDate 2009
url http://hdl.handle.net/10356/16561
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