Modeling of continuous protein refolding processes

• Main Author: Herman Budiyanto.
• Other Authors: Arvind Rajendran
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology; DRNTU::Engineering::Chemical engineering::Biotechnological production
• Online Access: http://hdl.handle.net/10356/16564
• Institution: Nanyang Technological University

Kinetic models of refolding and aggregation of bovine serum albumin (BSA) protein in solution and solid phases were developed. The rate constants of refolding and aggregation were obtained by fitting literature data with kinetic models of linearized refolding yield equation in batch reactor as a fun...