Unravelling human embryonic macrophage development using single cell sequencing and induced pluripotent stem cell models

• Main Author: Lee, Christopher Zhe Wei
• Other Authors: Su I-Hsin
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Biological sciences::Microbiology::Immunology
• Online Access: https://hdl.handle.net/10356/165650
• Institution: Nanyang Technological University

Macrophages are resident mononuclear phagocytes of the innate immune system whose primary functions include the phagocytosis and clearance of cellular debris, engulfment of pathogens and other foreign particulates, and regulation of inflammation. Of the myriad functions performed by macrophages, the...