Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells.

• Main Author: Polimyr Caesar Dave Pelisco Dingal.
• Other Authors: Chang Wook, Matthew
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnological production
• Online Access: http://hdl.handle.net/10356/16584
• Institution: Nanyang Technological University

Cystic fibrosis and rampant urogenital infections, caused by increasingly resistant microbial biofilms, call for more creative anti-infective systems. This study investigated the in vitro efficacy of levofloxacin (LEV)–loaded poly(D,L-lactide-co-glycolide) (PLGA) and poly-ε-caprolactone (PCL) nanopo...