Targeted drug discovery with adversarial graph autoencoders conditioned on gene expression data

• Main Author: Ong, Hiok Hian
• Other Authors: Jagath C Rajapakse
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Engineering::Computer science and engineering::Computing methodologies::Artificial intelligence; Science::Medicine::Pharmacy::Pharmaceutical technology
• Online Access: https://hdl.handle.net/10356/166090
• Institution: Nanyang Technological University

Drug discovery has long been an expensive and inefficient process due to the vast chemical compound search space. This process has been iteratively sharpened and refined using computational approaches in order to narrow the scope of search. Separately, machine learning, in particular deep learnin...