Protein profile in cells exposed to nonthermal radiofrequency field.

This project focus on the in vitro study of changes in protein profile in cells after exposure to radiofrequency from telecommunication devices and evaluate the change in protein profile with relevance to the effects on human health. The experiment was conducted at 37oC (±0.5oC) and the cell samples...

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主要作者: Xu, Lanbing.
其他作者: Chen Wei Ning, William
格式: Final Year Project
語言:English
出版: 2009
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在線閱讀:http://hdl.handle.net/10356/16630
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機構: Nanyang Technological University
語言: English
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spelling sg-ntu-dr.10356-166302023-03-03T15:41:24Z Protein profile in cells exposed to nonthermal radiofrequency field. Xu, Lanbing. Chen Wei Ning, William School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biotechnology This project focus on the in vitro study of changes in protein profile in cells after exposure to radiofrequency from telecommunication devices and evaluate the change in protein profile with relevance to the effects on human health. The experiment was conducted at 37oC (±0.5oC) and the cell samples were subjected to 10 or 40 minutes of exposure to radiofrequency of GSM 900MHz at 41V/m. Using LC/MS, the proteins present in the cell samples were analyzed and the protein concentration of radiated cells were compared against sham samples. There were visible changes in relative abundance of Histone 2A and 4, which can be linked to possible DNA damages. However, there were no evidence of changed protein level in metabolic proteins and it is concluded that there is no short term non-thermal effect of radiofrequency field on cells. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-27T07:41:15Z 2009-05-27T07:41:15Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16630 en Nanyang Technological University 73 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering::Biotechnology
spellingShingle DRNTU::Engineering::Chemical engineering::Biotechnology
Xu, Lanbing.
Protein profile in cells exposed to nonthermal radiofrequency field.
description This project focus on the in vitro study of changes in protein profile in cells after exposure to radiofrequency from telecommunication devices and evaluate the change in protein profile with relevance to the effects on human health. The experiment was conducted at 37oC (±0.5oC) and the cell samples were subjected to 10 or 40 minutes of exposure to radiofrequency of GSM 900MHz at 41V/m. Using LC/MS, the proteins present in the cell samples were analyzed and the protein concentration of radiated cells were compared against sham samples. There were visible changes in relative abundance of Histone 2A and 4, which can be linked to possible DNA damages. However, there were no evidence of changed protein level in metabolic proteins and it is concluded that there is no short term non-thermal effect of radiofrequency field on cells.
author2 Chen Wei Ning, William
author_facet Chen Wei Ning, William
Xu, Lanbing.
format Final Year Project
author Xu, Lanbing.
author_sort Xu, Lanbing.
title Protein profile in cells exposed to nonthermal radiofrequency field.
title_short Protein profile in cells exposed to nonthermal radiofrequency field.
title_full Protein profile in cells exposed to nonthermal radiofrequency field.
title_fullStr Protein profile in cells exposed to nonthermal radiofrequency field.
title_full_unstemmed Protein profile in cells exposed to nonthermal radiofrequency field.
title_sort protein profile in cells exposed to nonthermal radiofrequency field.
publishDate 2009
url http://hdl.handle.net/10356/16630
_version_ 1759858318822604800