Chitosan-carrageenan polyelectrolyte complex matrix as new protein/peptide drug carrier.

• Main Author: Chow, Sharan Mei Wei.
• Other Authors: Wang Kean
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: http://hdl.handle.net/10356/16638
• Institution: Nanyang Technological University

The oral route administration of protein and peptide drug has been limited by low bioavailability due to extensive hydrolysis and proteolytic enzymes activity in the gastrointestinal (GI) tract. Hence, chitosan-κ-carrageenan polyelectrolyte complex matrix that exhibit pH-dependent swelling character...