Functional dissection of membrane contacts sites in neuronal health in C. elegans

• Main Author: Nur Raihanah Binte Mohd Harion
• Other Authors: Yasunori Saheki
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Biological sciences::Molecular biology; Science::Biological sciences::Genetics
• Online Access: https://hdl.handle.net/10356/166597
• Institution: Nanyang Technological University

In neurons, the endoplasmic reticulum (ER) extends throughout all cellular processes, forming multiple contacts with the plasma membrane (PM) to fine-tune neuronal physiology. In my thesis project, I used the C. elegans DA9 motor neuron as my model system to explore the molecular mechanisms that are...