Diazirine photodissociation and solvent effects

• Main Author: Goh, Chen Yee
• Other Authors: Terry W.J. Steele
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Engineering::Materials
• Online Access: https://hdl.handle.net/10356/166671
• Institution: Nanyang Technological University

Carbene-based bioadhesive, CaproGlu involves the use of UVA active trifluoromethyl phenyl diazirine (TPD) as a precursor for reactive carbene to provide adhesion property. However, photolysis of TPD generates both diazoalkane and carbene species in ratio of 35:65. The effects of how solvent polarity...