Conformal microfluidics devices fabrication for sweat collection and detection

Sweat is an ideal substance for the continuous monitoring of various biomarkers due to its non invasive and easily accessible nature (Mena-Bravo & Luque de Castro, 2014). By monitoring these biomarkers in sweat, it becomes possible to detect numerous chronic health conditions such as diabete...

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Main Author: Lim, Gibson Zi Yang
Other Authors: Li King Ho Holden
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2023
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Online Access:https://hdl.handle.net/10356/166782
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-1667822023-05-13T16:51:41Z Conformal microfluidics devices fabrication for sweat collection and detection Lim, Gibson Zi Yang Li King Ho Holden School of Mechanical and Aerospace Engineering Singapore Institute of Manufacturing Technology HoldenLi@ntu.edu.sg Engineering::Mechanical engineering Sweat is an ideal substance for the continuous monitoring of various biomarkers due to its non invasive and easily accessible nature (Mena-Bravo & Luque de Castro, 2014). By monitoring these biomarkers in sweat, it becomes possible to detect numerous chronic health conditions such as diabetes, stress levels, and acute conditions like dehydration and muscle fatigue (Chung et al., 2019). The objective of this project is to create a solution that can design and fabricate conformal microfluidic devices for sweat sensing. The majority of sweat detection devices are currently made of PDMS (Polydimethylsiloxane), which presents a challenge in creating a thin and flexible layer suitable for mass production. An alternative approach involves the use of flexible printed circuit boards (PCBs) and electrochemical sensors, but this method is complex and time-consuming due to the fragility of the PCBs (Gao et al., 2016). This report aims to introduce an innovative manufacturing process that enables the creation of conformal microfluidic devices for sweat sensing. The manufacturing process for the conformal microfluidic devices for sweat sensing will involve various techniques, including laser cutting, hot embossing, and surface modification, to create enclosed microfluidic channels using thermoplastic materials that are suitable for mass production. Additionally, the integration of colorimetric hydrogel sensors will be studied to enable visual representation of the results through the naked eye or smartphone Bachelor of Engineering (Mechanical Engineering) 2023-05-12T08:26:16Z 2023-05-12T08:26:16Z 2023 Final Year Project (FYP) Lim, G. Z. Y. (2023). Conformal microfluidics devices fabrication for sweat collection and detection. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/166782 https://hdl.handle.net/10356/166782 en A030 application/pdf Nanyang Technological University
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Mechanical engineering
spellingShingle Engineering::Mechanical engineering
Lim, Gibson Zi Yang
Conformal microfluidics devices fabrication for sweat collection and detection
description Sweat is an ideal substance for the continuous monitoring of various biomarkers due to its non invasive and easily accessible nature (Mena-Bravo & Luque de Castro, 2014). By monitoring these biomarkers in sweat, it becomes possible to detect numerous chronic health conditions such as diabetes, stress levels, and acute conditions like dehydration and muscle fatigue (Chung et al., 2019). The objective of this project is to create a solution that can design and fabricate conformal microfluidic devices for sweat sensing. The majority of sweat detection devices are currently made of PDMS (Polydimethylsiloxane), which presents a challenge in creating a thin and flexible layer suitable for mass production. An alternative approach involves the use of flexible printed circuit boards (PCBs) and electrochemical sensors, but this method is complex and time-consuming due to the fragility of the PCBs (Gao et al., 2016). This report aims to introduce an innovative manufacturing process that enables the creation of conformal microfluidic devices for sweat sensing. The manufacturing process for the conformal microfluidic devices for sweat sensing will involve various techniques, including laser cutting, hot embossing, and surface modification, to create enclosed microfluidic channels using thermoplastic materials that are suitable for mass production. Additionally, the integration of colorimetric hydrogel sensors will be studied to enable visual representation of the results through the naked eye or smartphone
author2 Li King Ho Holden
author_facet Li King Ho Holden
Lim, Gibson Zi Yang
format Final Year Project
author Lim, Gibson Zi Yang
author_sort Lim, Gibson Zi Yang
title Conformal microfluidics devices fabrication for sweat collection and detection
title_short Conformal microfluidics devices fabrication for sweat collection and detection
title_full Conformal microfluidics devices fabrication for sweat collection and detection
title_fullStr Conformal microfluidics devices fabrication for sweat collection and detection
title_full_unstemmed Conformal microfluidics devices fabrication for sweat collection and detection
title_sort conformal microfluidics devices fabrication for sweat collection and detection
publisher Nanyang Technological University
publishDate 2023
url https://hdl.handle.net/10356/166782
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