Mechanism of telomere maintenance: HP1α mediates liquid-liquid phase separation of telomeric nucleosome array
Heterochromatin protein 1 (HP1) is a highly conserved protein playing a critical role in the organisation and maintenance of the heterochromatic state. Dysregulation of HP1 have been shown to have downstream implications on ageing and cancer. Understanding the interaction between HP1α, a paralog of...
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| Format: | Final Year Project |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/166891 |
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| Institution: | Nanyang Technological University |
| Language: | English |