Mechanism of telomere maintenance: HP1α mediates liquid-liquid phase separation of telomeric nucleosome array

• المؤلف الرئيسي: Putri, Dhira Anindya
• مؤلفون آخرون: Lars Nordenskiöld
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/166891
• المؤسسة: Nanyang Technological University

Heterochromatin protein 1 (HP1) is a highly conserved protein playing a critical role in the organisation and maintenance of the heterochromatic state. Dysregulation of HP1 have been shown to have downstream implications on ageing and cancer. Understanding the interaction between HP1α, a paralog of...