Enantioseparation of racemic compounds in reserved phase liquid chromatography using cationic β-cyclodextrin as chiral stationary phase.

• Main Author: Khoo, Linda Wei Ling.
• Other Authors: Ng Siu Choon
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Chemistry::Analytical chemistry::Chromatography
• Online Access: http://hdl.handle.net/10356/16826
• Institution: Nanyang Technological University

Two novel chiral stationary phases (CSP 1: dimethylbutadiene and CSP 2: methylmethacylate cationic phenylcarbamated-β-cyclodextrin) (Figure 1) were developed and immobilized at the C-6 position of cyclodextrin ring via polymerization. This positively charged imidazole was used to elucidate the influ...