Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study

This secondary data analysis study is interested in examining: (1) the differences in reward sensitivity between ADHD subjects and controls, (2) ADHD-related alterations in the functional connectivity of resting state neural networks - salience network (SN), default mode network (DMN) and executive...

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Main Author: Bai, Shifan
Other Authors: Annabel Chen Shen-Hsing
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2023
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Online Access:https://hdl.handle.net/10356/168525
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1685252023-06-18T15:32:21Z Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study Bai, Shifan Annabel Chen Shen-Hsing School of Social Sciences AnnabelChen@ntu.edu.sg Social sciences::Psychology This secondary data analysis study is interested in examining: (1) the differences in reward sensitivity between ADHD subjects and controls, (2) ADHD-related alterations in the functional connectivity of resting state neural networks - salience network (SN), default mode network (DMN) and executive control network (ECN), and (3) the relationship of the salience network with regards to reward signalling and sensitivity. Methods: Specifically, this study will conduct a group ICA analysis on resting state fMRI data, followed by univariate analyses using the MANCOVAN toolbox in GIFTICA to study the effect of group on functional connectivity of the resting state networks. Whole brain analysis was then conducted using SPM12 to further locate significant effect of group on activations within resting state networks. Finally, correlational analyses between salience network functional connectivity and the Sensitivity to Reward (SR) indices from the Sensitivity to Punishment and Sensitivity to Reward Questionnaire were applied. Results: No significant difference in reward sensitivity was found between groups. There was partial support for significant effect of group on aberrant functional connectivity within resting-state networks, and no significant correlation was found between salience network connectivity and reward sensitivity. Bachelor of Social Sciences in Psychology 2023-06-14T01:54:25Z 2023-06-14T01:54:25Z 2023 Final Year Project (FYP) Bai, S. (2023). Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/168525 https://hdl.handle.net/10356/168525 en application/pdf Nanyang Technological University
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Social sciences::Psychology
spellingShingle Social sciences::Psychology
Bai, Shifan
Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
description This secondary data analysis study is interested in examining: (1) the differences in reward sensitivity between ADHD subjects and controls, (2) ADHD-related alterations in the functional connectivity of resting state neural networks - salience network (SN), default mode network (DMN) and executive control network (ECN), and (3) the relationship of the salience network with regards to reward signalling and sensitivity. Methods: Specifically, this study will conduct a group ICA analysis on resting state fMRI data, followed by univariate analyses using the MANCOVAN toolbox in GIFTICA to study the effect of group on functional connectivity of the resting state networks. Whole brain analysis was then conducted using SPM12 to further locate significant effect of group on activations within resting state networks. Finally, correlational analyses between salience network functional connectivity and the Sensitivity to Reward (SR) indices from the Sensitivity to Punishment and Sensitivity to Reward Questionnaire were applied. Results: No significant difference in reward sensitivity was found between groups. There was partial support for significant effect of group on aberrant functional connectivity within resting-state networks, and no significant correlation was found between salience network connectivity and reward sensitivity.
author2 Annabel Chen Shen-Hsing
author_facet Annabel Chen Shen-Hsing
Bai, Shifan
format Final Year Project
author Bai, Shifan
author_sort Bai, Shifan
title Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
title_short Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
title_full Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
title_fullStr Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
title_full_unstemmed Functional connectivity of resting-state networks in ADHD and salience reward processing: a secondary data analysis study
title_sort functional connectivity of resting-state networks in adhd and salience reward processing: a secondary data analysis study
publisher Nanyang Technological University
publishDate 2023
url https://hdl.handle.net/10356/168525
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